| 04 | Anna Cockrell |  | 51.87 | | 8 ago 2024 | Stade de France, Paris (FRA) |
| 05 | Jasmine Jones | | 52.08 | | 19 set 2025 | National Stadium, Tokyo (JPN) |
| 06 | Yulia Pechonkina |  | 52.34 | | 8 ago 2003 | Tula (RUS) |
| 07 | Shamier Little | | 52.39 | | 4 lug 2021 | Olympiastadion, Stockholm (SWE) |
| 08 | Melaine Walker |  | 52.42 | | 20 ago 2009 | Olympiastadion, Berlin (GER) |
| 09 | Savannah Sutherland |  | 52.46 | | 14 giu 2025 | Hayward Field, Eugene, OR (USA) |
| 10 | Lashinda Demus | | 52.47 | | 1 set 2011 | DS, Daegu (KOR) |
| 11 | Rushell Clayton | | 52.51 | | 28 giu 2024 | National Stadium, Kingston (JAM) |
| 12 | Kim Batten | | 52.61 | | 11 ago 1995 | Ullevi Stadium, Göteborg (SWE) |
| 13 | Tonja Buford-Bailey | | 52.62 | | 11 ago 1995 | Ullevi Stadium, Göteborg (SWE) |
| 14 | Gianna Woodruff |  | 52.66 | | 17 set 2025 | National Stadium, Tokyo (JPN) |
| 15 | Sally Gunnell |  | 52.74 | | 19 ago 1993 | Gottlieb-Daimler Stadion, Stuttgart (GER) |
| 16 | Fani Chalkia |  | 52.77 | | 22 ago 2004 | Olympic Stadium, Athina (GRE) |
| 17 | Sandra Farmer-Patrick | | 52.79 | | 19 ago 1993 | Gottlieb-Daimler Stadion, Stuttgart (GER) |
| 17 | Kaliese Spencer | | 52.79 | | 5 ago 2011 | Crystal Palace, London (GBR) |
| 19 | Deon Hemmings | | 52.82 | | 31 lug 1996 | Olympic Stadium, Atlanta, GA (USA) |
| 20 | Zuzana Hejnová |  | 52.83 | | 15 ago 2013 | Luzhniki Stadion, Moskva (RUS) |
| 21 | Daimí Pernía |  | 52.89 | | 25 ago 1999 | La Cartuja, Sevilla (ESP) |
| 22 | Nezha Bidouane |  | 52.90 | | 25 ago 1999 | La Cartuja, Sevilla (ESP) |
| 23 | Natalya Antyukh | | 52.92 | | 30 lug 2010 | Estadio Olímpico, Barcelona (ESP) |
| 24 | Marina Stepanova | | 52.94 | | 17 set 1986 | Tashkent (UZB) |
| 25 | Kori Carter | | 52.95 | | 25 giu 2017 | Sacramento, CA (USA) |
| 25 | Sheena Johnson-Tosta | | 52.95 | | 11 lug 2004 | Sacramento, CA (USA) |
| 27 | Anna Ryzhykova |  | 52.96 | | 4 lug 2021 | Olympiastadion, Stockholm (SWE) |
| 28 | Shiann Salmon | | 52.97 | | 5 set 2024 | Letzigrund, Zürich (SUI) |
| 29 | Emma Zapletalová |  | 53.00 | | 19 set 2025 | National Stadium, Tokyo (JPN) |
| 30 | Irina Privalova | | 53.02 | | 27 set 2000 | Olympic Stadium, Sydney (AUS) |
| 31 | Britton Wilson | | 53.08 | | 25 giu 2022 | Hayward Field, Eugene, OR (USA) |
| 31 | Janieve Russell | | 53.08 | | 4 ago 2021 | National Stadium, Tokyo (JPN) |
| 33 | Kemi Adekoya |  | 53.09 | | 24 ago 2023 | Nemzeti Atlétikai Központ, Budapest (HUN) |
| 34 | Tatyana Ledovskaya | | 53.11 | | 29 ago 1991 | National Stadium, Tokyo (JPN) |
| 34 | Ashley Spencer | | 53.11 | | 25 giu 2017 | Sacramento, CA (USA) |
| 36 | Georganne Moline | | 53.14 | | 25 giu 2017 | Sacramento, CA (USA) |
| 37 | Debbie Flintoff-King |  | 53.17 | | 28 set 1988 | Olympic Stadium, Seoul (KOR) |
| 38 | Josanne Lucas |  | 53.20 | | 20 ago 2009 | Olympiastadion, Berlin (GER) |
| 39 | Marie-José Pérec |  | 53.21 | | 16 ago 1995 | Zürich (SUI) |
| 40 | Jana Pittman | | 53.22 | | 28 ago 2003 | Stade de France, Paris-St-Denis (FRA) |
| 41 | Sabine Busch |  | 53.24 | | 21 ago 1987 | Potsdam (GDR) |
| 42 | Ionela Ţirlea-Manolache |  | 53.25 | | 7 lug 1999 | Stadio Olimpico, Roma (ITA) |
| 43 | Andrenette Knight | | 53.26 | | 18 lug 2023 | Bregyó Athletic Center, Székesfehérvár (HUN) |
| 44 | Tiffany Williams | | 53.28 | | 24 giu 2007 | Indianapolis, IN (USA) |
| 45 | Sandra Cummings-Glover | | 53.32 | | 13 ago 2005 | Olympiastadion, Helsinki (FIN) |
| 46 | Brenda Taylor | | 53.36 | | 11 lug 2004 | Sacramento, CA (USA) |
| 46 | Andrea Blackett |  | 53.36 | | 25 ago 1999 | La Cartuja, Sevilla (ESP) |
| 48 | Tetyana Tereshchuk-Antipova | | 53.37 | | 22 ago 2004 | Olympic Stadium, Athina (GRE) |
| 49 | Rachel Glenn | | 53.46 | | 30 giu 2024 | Hayward Field, Eugene, OR (USA) |
| 50 | Janeene Vickers | | 53.47 | | 29 ago 1991 | National Stadium, Tokyo (JPN) |
