| 295 | Brionna Thomas |  | 50.78 | | Jun 9, 2018 | Eugene, OR (USA) |
| 295 | Tatyana Levina |  | 50.78 | | Aug 2, 2007 | Tula (RUS) |
| 295 | Danijela Grgić |  | 50.78 | | Aug 17, 2006 | Chaoyang Sport Center, Beijing (CHN) |
| 304 | Hima Das |  | 50.79 | | Aug 26, 2018 | Jakarta (INA) |
| 304 | Natalya Ivanova | | 50.79 | | Jul 31, 2004 | Tula (RUS) |
| 304 | Zoe Sherar |  | 50.79 | | Jun 4, 2024 | Alumni Stadium, Guelph (CAN) |
| 304 | Taylor Manson | | 50.79 | | Jun 20, 2021 | Hayward Field, Eugene, OR (USA) |
| 308 | Inna Yevseyeva | | 50.80 | | - | - |
| 308 | Eleni Artymata |  | 50.80 | | Aug 4, 2021 | National Stadium, Tokyo (JPN) |
| 308 | Naomi Van Den Broeck |  | 50.80 | | Jun 21, 2024 | Estadio Vallehermoso, Madrid (ESP) |
| 311 | Zenéy Van Der Walt |  | 50.81 | | Apr 12, 2023 | Bestmed Tuks Stadium, Pretoria (RSA) |
| 312 | Rositsa Stamenova |  | 50.82 | | Aug 16, 1984 | Praha (TCH) |
| 312 | Cathy Rattray-Williams |  | 50.82 | | Sep 25, 1988 | Olympic Stadium, Seoul (KOR) |
| 312 | Yuliana Marinova | | 50.82 | | Aug 15, 1987 | Sofia (BUL) |
| 312 | Anna Hall | | 50.82 | | Jun 9, 2023 | Stade Charléty, Paris (FRA) |
| 312 | Kaelin Roberts | | 50.82 | | May 29, 2021 | Cushing Stadium, College Station, TX (USA) |
| 312 | Lee Mcconnell |  | 50.82 | | Sep 20, 2002 | CM, Madrid (ESP) |
| 318 | Lina Esther Licona Torres |  | 50.83 | | Jun 20, 2024 | Padre Carolo, Quito (ECU) |
| 318 | Gisela-Maria Kinzel |  | 50.83 | | Aug 15, 1986 | Berlin (GER) |
| 318 | Gunta Vaičule |  | 50.83 | | Jun 29, 2024 | Jāņa Daliņa Stadium, Valmiera (LAT) |
| 318 | Tiandra Ponteen |  | 50.83 | | Jun 11, 2005 | Sacramento, CA (USA) |
| 318 | Mariya Lisnichenko | | 50.83 | | Jul 29, 2004 | Tula (RUS) |
| 318 | Allison Beckford | | 50.83 | | Jun 1, 2002 | Baton Rouge, LA (USA) |
| 324 | Regina George |  | 50.84 | | Aug 11, 2013 | Luzhniki Stadion, Moskva (RUS) |
| 324 | Denisa Rosolová |  | 50.84 | | May 31, 2011 | Mestský Stadion, Ostrava (CZE) |
| 324 | Floria Guei |  | 50.84 | | Jun 5, 2016 | Alexander Stadium, Birmingham (GBR) |
| 324 | Shana Cox | | 50.84 | | May 31, 2008 | Tallahassee, FL (USA) |
| 324 | Emily Newnham | | 50.84 | | Jun 27, 2025 | Estadio Vallehermoso, Madrid (ESP) |
| 324 | Shae Anderson | | 50.84 | | Jun 20, 2021 | Hayward Field, Eugene, OR (USA) |
| 330 | Jitka Burianová | | 50.85 | | Sep 23, 2000 | Olympic Stadium, Sydney (AUS) |
| 330 | Silke-Beate Knoll | | 50.85 | | Jul 1, 1995 | Bremen (GER) |
| 332 | Imke Vervaet | | 50.86 | | Jun 28, 2025 | Atletski stadion Poljane, Maribor (SLO) |
| 332 | Davita Prendergast | | 50.86 | | Jun 26, 2011 | Kingston (JAM) |
| 334 | Magdalena Nedelcu |  | 50.87 | | Jul 31, 1992 | Bucureşti (ROU) |
| 334 | Anyika Onuora | | 50.87 | | Aug 25, 2015 | National Stadium, Beijing (CHN) |
| 334 | Bobby-Gaye Wilkins-Gooden | | 50.87 | | Jun 28, 2008 | Kingston (JAM) |
| 334 | Kyra Constantine | | 50.87 | | Jun 12, 2021 | Hayward Field, Eugene, OR (USA) |
| 334 | Me'Lisa Barber | | 50.87 | | Jun 1, 2002 | Baton Rouge, LA (USA) |
| 334 | Zulia Calatayud |  | 50.87 | | Jun 30, 2001 | Alcalá de Henáres (ESP) |
| 340 | Diamond Dixon | | 50.88 | | Jun 24, 2012 | Hayward Field, Eugene, OR (USA) |
| 340 | Rita Wilden | | 50.88 | | Sep 4, 1974 | Stadio Olimpico, Roma (ITA) |
| 342 | Florence Griffith Joyner | | 50.89 | | Jun 8, 1985 | Los Angeles, CA (USA) |
| 342 | Folashade Abugan | | 50.89 | | May 2, 2008 | Addis Ababa (ETH) |
| 344 | Youlanda Warren | | 50.90 | | Jun 17, 1996 | Atlanta, GA (USA) |
| 344 | Sheila Ingram | | 50.90 | | Jul 29, 1976 | Olympic Stadium, Montréal (CAN) |
| 346 | Natassha Mcdonald | | 50.91 | | May 15, 2021 | Cushing Stadium, College Station, TX (USA) |
| 346 | Nadezhda Lalina | | 50.91 | | May 24, 1983 | Krasnodar (URS) |
| 346 | Madison Whyte | | 50.91 | | Mar 29, 2025 | LSU Bernie Moore Stadium, Baton Rouge, LA (USA) |
| 346 | Corinna Schwab | | 50.91 | | Jun 25, 2022 | Olympiastadion, Berlin (GER) |
| 346 | Lyudmila Chernova | | 50.91 | | May 24, 1983 | Krasnodar (URS) |
