| 250 | Hazel-Ann Regis |  | 50.64 | | May 16, 2004 | Oxford (GBR) |
| 250 | Daina Harper |  | 50.64 | | Jun 24, 2017 | Sacramento, CA (USA) |
| 250 | Karin Janke |  | 50.64 | | Aug 11, 1990 | Düsseldorf (GER) |
| 250 | Brianna White | | 50.64 | | May 25, 2024 | Un. of Kentucky Outdoor Track Facility, Lexington, KY (USA) |
| 255 | Yelena Ruzina |  | 50.65 | | Jul 6, 1990 | Kiev (URS) |
| 256 | Nadia Davy |  | 50.66 | | Jun 14, 2003 | Sacramento, CA (USA) |
| 256 | Rachel Joseph | | 50.66 | | May 31, 2025 | Cushing Stadium, College Station, TX (USA) |
| 256 | Miranda Charlene Coetzee |  | 50.66 | | Aug 6, 2024 | Stade de France, Paris (FRA) |
| 256 | Irina Rosikhina | | 50.66 | | Jul 30, 2004 | Tula (RUS) |
| 260 | Anna Tkach | | 50.67 | | Jul 23, 2000 | Tula (RUS) |
| 260 | Tracey Barnes | | 50.67 | | Jun 27, 1998 | Kingston (JAM) |
| 260 | Shannelle Porter | | 50.67 | | Jul 7, 1996 | Padova (ITA) |
| 263 | Javonya Valcourt |  | 50.68 | | Apr 19, 2025 | Percy Beard Track, Gainesville, FL (USA) |
| 263 | Tovea Jenkins | | 50.68 | | Jun 27, 2021 | National Stadium, Kingston (JAM) |
| 263 | Tatyana Roslanova |  | 50.68 | | Jun 5, 2004 | Almaty (KAZ) |
| 266 | Sharrika Barnett | | 50.69 | | May 13, 2018 | Knoxville, TN (USA) |
| 266 | Mireille Nguimgo |  | 50.69 | | Aug 13, 2000 | La Chaux-de-Fonds (SUI) |
| 266 | Paula Sevilla |  | 50.69 | | Sep 14, 2025 | National Stadium, Tokyo (JPN) |
| 266 | Aminatou Seyni |  | 50.69 | | Aug 23, 2018 | Rovereto (ITA) |
| 266 | Antonina Yefremova |  | 50.69 | | May 31, 2011 | Yalta (UKR) |
| 271 | Gabriele Kotte | | 50.70 | | Aug 12, 1979 | Karl Marx Stadt (GDR) |
| 271 | Genowefa Blaszak |  | 50.70 | | Aug 15, 1986 | Berlin (GER) |
| 273 | Aliann Tabitha Pompey |  | 50.71 | | Aug 16, 2009 | Olympiastadion, Berlin (GER) |
| 273 | Allison Curbishley |  | 50.71 | | Sep 18, 1998 | Kuala Lumpur (MAS) |
| 273 | Patricia Hall | | 50.71 | | Jun 7, 2012 | Bislett Stadion, Oslo (NOR) |
| 273 | Vineta Ikauniece | | 50.71 | | Sep 4, 1988 | Moskva (URS) |
| 273 | Sharlene Mawdsley |  | 50.71 | | Aug 5, 2024 | Stade de France, Paris (FRA) |
| 273 | Patience Okon George |  | 50.71 | | Sep 15, 2015 | Brazzaville (CGO) |
| 279 | Adri De Jongh-Schoeman | | 50.73 | | Apr 14, 1996 | Johannesburg (RSA) |
| 279 | Claudine Komgang-Fotsing | | 50.73 | | Jul 2, 2000 | Ciudad de México (MEX) |
| 279 | Joanne Cuddihy | | 50.73 | | Aug 27, 2007 | Yanmar Stadium Nagai, Osaka (JPN) |
| 279 | Yuliya Sotnikova | | 50.73 | | Jul 24, 2000 | Tula (RUS) |
| 283 | Suziann Reid | | 50.74 | | Jul 2, 1999 | Stade Olympique de la Pontaise, Lausanne (SUI) |
| 283 | Christine Mallard | | 50.74 | | Jul 9, 2023 | Hayward Field, Eugene, OR (USA) |
| 283 | Junelle Bromfield | | 50.74 | | Jun 29, 2024 | National Stadium, Kingston (JAM) |
| 286 | Ama Pipi | | 50.75 | | Jul 20, 2023 | Štadión SNP, Banská Bystrica (SVK) |
| 286 | Joslyn Hoyte-Smith | | 50.75 | | Jun 18, 1982 | London (GBR) |
| 288 | Keshia Kirtz | | 50.76 | | May 16, 2010 | Berkeley, CA (USA) |
| 288 | Anna Polinari |  | 50.76 | | Jun 27, 2025 | Estadio Vallehermoso, Madrid (ESP) |
| 288 | Janieve Russell | | 50.76 | | Jul 9, 2023 | National Stadium, Kingston (JAM) |
| 288 | Anneisha Mclaughlin-Whilby | | 50.76 | | Jun 25, 2017 | Kingston (JAM) |
| 288 | Emma Zapletalová |  | 50.76 | | Jun 28, 2025 | Atletski stadion Poljane, Maribor (SLO) |
| 293 | Lisanne De Witte |  | 50.77 | | Aug 11, 2018 | Olympiastadion, Berlin (GER) |
| 293 | Yelena Didilenko-Korban | | 50.77 | | Jul 27, 1983 | Leningrad (URS) |
| 295 | Olga Mineyeva | | 50.78 | | - | - |
| 295 | Gisela Anton | | 50.78 | | Jul 27, 1976 | Halle (GER) |
| 295 | Michelle Lock |  | 50.78 | | Aug 3, 1992 | Estadio Olímpico, Barcelona (ESP) |
| 295 | Leah Anderson | | 50.78 | | Jun 29, 2025 | National Stadium, Kingston (JAM) |
| 295 | Lina Nielsen | | 50.78 | | Jul 14, 2024 | Stade de La Charrière, La Chaux-de-Fonds (SUI) |
| 295 | Brionna Thomas | | 50.78 | | Jun 9, 2018 | Eugene, OR (USA) |
