| 548 | Na'Asha Robinson |  | 51.30 | | Jun 18, 2021 | Hayward Field, Eugene, OR (USA) |
| 548 | Megan Mcginnis | | 51.30 | | Jun 8, 2023 | Mike A. Myers Stadium, Austin, TX (USA) |
| 548 | Ellie Beer |  | 51.30 | | Jun 21, 2025 | Centre sportif Bout-du-Monde, Genève (SUI) |
| 548 | Dianna Proctor |  | 51.30 | | Jun 22, 2025 | Alumni Stadium, London (CAN) |
| 548 | Anna Gryc |  | 51.30 | | Jul 5, 2025 | Golęcin Stadion, Poznan (POL) |
| 556 | Kaelyaah Liburd |  | 51.31 | | May 31, 2025 | University of North Florda Jax Track at Hodges Stadium, Jacksonville, FL (USA) |
| 556 | Sharon Dabney | | 51.31 | | Jun 10, 1978 | Westwood, CA (USA) |
| 556 | Virna De Angeli |  | 51.31 | | Jun 17, 1997 | Bari (ITA) |
| 556 | Patrycja Wyciszkiewicz | | 51.31 | | Aug 24, 2015 | National Stadium, Beijing (CHN) |
| 556 | Naledi Lopang |  | 51.31 | | May 26, 2023 | National Stadium, Gaborone (BOT) |
| 556 | Aaliyah Pyatt | | 51.31 | | May 29, 2025 | Cushing Stadium, College Station, TX (USA) |
| 562 | Meleni Rodney |  | 51.32 | | May 16, 2021 | Katherine B. Loker Stadium, Los Angeles, CA (USA) |
| 562 | Kiah Williams | | 51.32 | | Apr 13, 2024 | Percy Beard Track, Gainesville, FL (USA) |
| 562 | Darya Terekhova |  | 51.32 | | Jul 23, 2009 | Cheboksary (RUS) |
| 562 | Elexis Guster | | 51.32 | | May 14, 2017 | Eugene, OR (USA) |
| 562 | Claudine Williams |  | 51.32 | | Aug 5, 1995 | Ullevi Stadium, Göteborg (SWE) |
| 562 | Anita Protti |  | 51.32 | | Jun 15, 1990 | Genève (SUI) |
| 562 | Pepa Pavlova |  | 51.32 | | Aug 11, 1986 | Budapest (HUN) |
| 569 | Zaya Akins | | 51.33 | | May 25, 2024 | Un. of Kentucky Outdoor Track Facility, Lexington, KY (USA) |
| 569 | Molly Killingbeck | | 51.33 | | Jun 11, 1983 | Calgary (CAN) |
| 571 | Lee Naylor | | 51.35 | | May 9, 1998 | Osaka (JPN) |
| 571 | Ester Goossens |  | 51.35 | | Jun 6, 1998 | Malmö (SWE) |
| 571 | Fanfang Bu |  | 51.35 | | Nov 18, 2001 | Guangzhou (CHN) |
| 571 | Anabel Medina Ventura |  | 51.35 | | May 11, 2024 | Pista de Atletismo da Universidade Federal do Mato Grosso, Cuiaba (BRA) |
| 571 | Takyera Roberson | | 51.35 | | Jun 24, 2017 | Sacramento, CA (USA) |
| 571 | Eva Santidrián |  | 51.35 | | Jun 28, 2025 | Pistas Universad de León, León (ESP) |
| 577 | Christine Marquardt |  | 51.36 | | Jul 2, 1978 | Leipzig (GER) |
| 577 | Catherine Murphy |  | 51.36 | | Jul 27, 2002 | Manchester (GBR) |
| 577 | Robin Reynolds | | 51.36 | | Jun 11, 2014 | Eugene, OR (USA) |
| 577 | Margaret Vanessa Barrie |  | 51.36 | | May 13, 2018 | Bloomington, IN (USA) |
| 577 | Amy Allcock | | 51.36 | | Jul 22, 2018 | Olympic Stadium, London (GBR) |
| 582 | Mercedes Álvarez |  | 51.37 | | Jun 4, 1983 | Bucureşti (ROU) |
| 582 | Maria de Lurdes Mutola |  | 51.37 | | Aug 2, 1994 | Stade Louis II, Monaco (MON) |
| 582 | Daye Shon Roberson | | 51.37 | | May 29, 2015 | Austin, TX (USA) |
| 582 | June Griffith |  | 51.37 | | May 19, 1979 | Durham, NC (USA) |
| 586 | Lyubov Gurina | | 51.38 | | Jun 10, 1983 | Moskva (URS) |
| 586 | Inez Turner-Gray | | 51.38 | | Jun 27, 1996 | Kingston (JAM) |
| 586 | Lilla Mcmillan | | 51.38 | | May 15, 2016 | Orlando, FL (USA) |
| 586 | Yelena Vinogradova-Petushinskaya | | 51.38 | | Jul 6, 1990 | Kiev (URS) |
| 590 | Ebony Eutsey | | 51.39 | | Jun 11, 2016 | Kingston (JAM) |
| 590 | Alicja Wrona-Kutrzepa | | 51.39 | | Jul 5, 2025 | Golęcin Stadion, Poznan (POL) |
| 590 | Nancy Mcleon | | 51.39 | | Aug 5, 1995 | Ullevi Stadium, Göteborg (SWE) |
| 590 | Racheal Nachula |  | 51.39 | | May 2, 2008 | Addis Ababa (ETH) |
| 590 | Carol Rodríguez |  | 51.39 | | May 3, 2008 | Los Angeles, CA (USA) |
| 590 | Ajoke Odumosu |  | 51.39 | | Aug 15, 2008 | National Stadium, Beijing (CHN) |
| 590 | Margaret Nyairera Wambui |  | 51.39 | | May 28, 2016 | Nairobi (KEN) |
| 590 | Georganne Moline | | 51.39 | | - | - |
| 598 | Titania Markland | | 51.40 | | May 13, 2018 | Bloomington, IN (USA) |
| 598 | Maureen Jelagat Maiyo | | 51.40 | | Aug 24, 2015 | National Stadium, Beijing (CHN) |
| 598 | Verona Elder | | 51.40 | | May 22, 1976 | Kiev (URS) |
