| 251 | Syota Fuchigami |  | 48.78 | | Sep 21, 2024 | Todoroki Stadium, Kawasaki (JPN) |
| 251 | Zhiyu Xie |  | 48.78 | | Aug 4, 2023 | Shuangliu Sports Centre, Chengdu (CHN) |
| 251 | Michal Rada |  | 48.78 | | Aug 9, 2025 | Ratinan Stadion, Tampere (FIN) |
| 251 | Aleksandr Kharlov |  | 48.78 | | Jun 20, 1983 | Moskva (URS) |
| 255 | Lueroy Colquhoun |  | 48.79 | | Jun 25, 2005 | Kingston (JAM) |
| 255 | Rasheeme Griffith |  | 48.79 | | May 9, 2024 | Percy Beard Track, Gainesville, FL (USA) |
| 255 | Leonardo Ledgister | | 48.79 | | May 29, 2021 | Cushing Stadium, College Station, TX (USA) |
| 255 | Amaechi Morton |  | 48.79 | | Jun 8, 2012 | Des Moines, IA (USA) |
| 255 | Hiromu Yamauchi | | 48.79 | | Aug 3, 2025 | Hokuroku Park Athletic Field, Fujiyoshida (JPN) |
| 255 | Shakeem Hall-Smith |  | 48.79 | | May 31, 2024 | Edwin Moses Track, Atlanta, GA (USA) |
| 261 | Dharun Ayyasamy |  | 48.80 | | Mar 16, 2019 | Patiala (IND) |
| 261 | Niall Flannery |  | 48.80 | | Jun 17, 2014 | Mestský Stadion, Ostrava (CZE) |
| 261 | Kareem Archer | | 48.80 | | May 25, 1997 | Fairfax, VA (USA) |
| 261 | Athanasios Kalogiannis |  | 48.80 | | Jul 19, 1987 | Zagreb (CRO) |
| 265 | Lindsay Hanekom |  | 48.81 | | Apr 27, 2019 | Germiston (RSA) |
| 265 | Hannes Pienaar | | 48.81 | | Feb 15, 1986 | Pretoria (RSA) |
| 267 | Dennick Luke |  | 48.82 | | Aug 16, 2025 | Grand Bahama Sports Complex, Freeport (BAH) |
| 268 | Yacnier Luis González |  | 48.83 | | Jun 24, 2004 | La Habana (CUB) |
| 268 | Haruto Deguchi | | 48.83 | | May 12, 2024 | Yanmar Stadium Nagai, Osaka (JPN) |
| 268 | Shawn Rowe | | 48.83 | | Aug 1, 2021 | National Stadium, Tokyo (JPN) |
| 268 | Ricardo Cunningham | | 48.83 | | Jun 23, 2017 | Kingston (JAM) |
| 268 | Pat Mcghee |  | 48.83 | | Aug 11, 1988 | Sestriere (ITA) |
| 273 | Hideaki Kawamura | | 48.84 | | Sep 9, 2000 | Yokohama (JPN) |
| 273 | Miles Ukaoma | | 48.84 | | Jul 31, 2015 | Warri (NGR) |
| 273 | Rhys Williams | | 48.84 | | Jul 17, 2013 | Luzern (SUI) |
| 273 | Gianni Carabelli |  | 48.84 | | Jul 8, 2005 | Stadio Olimpico, Roma (ITA) |
| 277 | Drake Schneider | | 48.85 | | Apr 12, 2025 | Cregger Track, Columbia, SC (USA) |
| 277 | Ken Yoshizawa | | 48.85 | | Jul 10, 2004 | Fukuroi (JPN) |
| 277 | Corey Murdock | | 48.85 | | Jul 12, 1999 | Palma de Mallorca (ESP) |
| 280 | Fred Sharpe | | 48.86 | | May 18, 2003 | Knoxville, TN (USA) |
| 280 | Stéphane Caristan |  | 48.86 | | Aug 6, 1992 | Estadio Olímpico, Barcelona (ESP) |
| 282 | Zaid Abou Hamed |  | 48.87 | | Feb 20, 1999 | Sydney (AUS) |
| 282 | Sergio Fernández |  | 48.87 | | Aug 16, 2016 | Estádio Olímpico, Rio de Janeiro (BRA) |
| 282 | James Smith Ii | | 48.87 | | Apr 19, 2025 | Hilmer Lodge Stadium, Walnut, CA (USA) |
| 282 | Masaki Toyoda | | 48.87 | | May 9, 2021 | National Stadium, Tokyo (JPN) |
| 286 | Ricky Babineaux | | 48.88 | | Jul 10, 2016 | Hayward Field, Eugene, OR (USA) |
| 286 | Jonathan Williams |  | 48.88 | | Jul 14, 2007 | San Salvador (ESA) |
| 288 | Carsten Köhrbrück |  | 48.89 | | Aug 12, 1990 | Düsseldorf (GER) |
| 288 | Alex Knibbs | | 48.89 | | Jul 14, 2024 | Stade de La Charrière, La Chaux-de-Fonds (SUI) |
| 288 | Malik Metivier |  | 48.89 | | Jun 8, 2022 | Hayward Field, Eugene, OR (USA) |
| 288 | Jamele Mason |  | 48.89 | | Jun 8, 2012 | Des Moines, IA (USA) |
| 288 | Efekemo Okoro | | 48.89 | | Aug 24, 2024 | Manchester Regional Arena, Manchester (GBR) |
| 293 | Tyrece Hyman | | 48.90 | | Aug 20, 2025 | Parque Olímpico Pista De Atletismo, Luque, Asunción (PAR) |
| 293 | Barnabas Agui Kinyor |  | 48.90 | | Aug 3, 1992 | Estadio Olímpico, Barcelona (ESP) |
| 293 | Anthony Borsumato | | 48.90 | | Jul 14, 2002 | Birmingham (GBR) |
| 296 | Josè Bencosme De Leon | | 48.91 | | Jul 1, 2022 | Stade Complexe Olympique, Oran (ALG) |
| 296 | Marc Dollendorf |  | 48.91 | | Jul 31, 1996 | Olympic Stadium, Atlanta, GA (USA) |
| 296 | Ryan Hayden | | 48.91 | | Jun 16, 1995 | Sacramento, CA (USA) |
| 299 | Marthinus Kritzinger | | 48.92 | | Apr 11, 2003 | Durban (RSA) |
| 299 | Chieh Chen |  | 48.92 | | Apr 22, 2019 | Doha (QAT) |
