| 250 | Hazel-Ann Regis |  | 50.64 | | 16 may 2004 | Oxford (GBR) |
| 250 | Daina Harper |  | 50.64 | | 24 jun 2017 | Sacramento, CA (USA) |
| 250 | Karin Janke |  | 50.64 | | 11 ago 1990 | Düsseldorf (GER) |
| 250 | Brianna White | | 50.64 | | 25 may 2024 | Un. of Kentucky Outdoor Track Facility, Lexington, KY (USA) |
| 255 | Yelena Ruzina |  | 50.65 | | 6 jul 1990 | Kiev (URS) |
| 256 | Nadia Davy |  | 50.66 | | 14 jun 2003 | Sacramento, CA (USA) |
| 256 | Rachel Joseph | | 50.66 | | 31 may 2025 | Cushing Stadium, College Station, TX (USA) |
| 256 | Miranda Charlene Coetzee |  | 50.66 | | 6 ago 2024 | Stade de France, Paris (FRA) |
| 256 | Irina Rosikhina | | 50.66 | | 30 jul 2004 | Tula (RUS) |
| 260 | Anna Tkach | | 50.67 | | 23 jul 2000 | Tula (RUS) |
| 260 | Tracey Barnes | | 50.67 | | 27 jun 1998 | Kingston (JAM) |
| 260 | Shannelle Porter | | 50.67 | | 7 jul 1996 | Padova (ITA) |
| 263 | Javonya Valcourt |  | 50.68 | | 19 abr 2025 | Percy Beard Track, Gainesville, FL (USA) |
| 263 | Tovea Jenkins | | 50.68 | | 27 jun 2021 | National Stadium, Kingston (JAM) |
| 263 | Tatyana Roslanova |  | 50.68 | | 5 jun 2004 | Almaty (KAZ) |
| 266 | Sharrika Barnett | | 50.69 | | 13 may 2018 | Knoxville, TN (USA) |
| 266 | Mireille Nguimgo |  | 50.69 | | 13 ago 2000 | La Chaux-de-Fonds (SUI) |
| 266 | Paula Sevilla |  | 50.69 | | 14 sept 2025 | National Stadium, Tokyo (JPN) |
| 266 | Aminatou Seyni |  | 50.69 | | 23 ago 2018 | Rovereto (ITA) |
| 266 | Antonina Yefremova |  | 50.69 | | 31 may 2011 | Yalta (UKR) |
| 271 | Gabriele Kotte | | 50.70 | | 12 ago 1979 | Karl Marx Stadt (GDR) |
| 271 | Genowefa Blaszak |  | 50.70 | | 15 ago 1986 | Berlin (GER) |
| 273 | Aliann Tabitha Pompey |  | 50.71 | | 16 ago 2009 | Olympiastadion, Berlin (GER) |
| 273 | Allison Curbishley |  | 50.71 | | 18 sept 1998 | Kuala Lumpur (MAS) |
| 273 | Patricia Hall | | 50.71 | | 7 jun 2012 | Bislett Stadion, Oslo (NOR) |
| 273 | Vineta Ikauniece | | 50.71 | | 4 sept 1988 | Moskva (URS) |
| 273 | Sharlene Mawdsley |  | 50.71 | | 5 ago 2024 | Stade de France, Paris (FRA) |
| 273 | Patience Okon George |  | 50.71 | | 15 sept 2015 | Brazzaville (CGO) |
| 279 | Adri De Jongh-Schoeman | | 50.73 | | 14 abr 1996 | Johannesburg (RSA) |
| 279 | Claudine Komgang-Fotsing | | 50.73 | | 2 jul 2000 | Ciudad de México (MEX) |
| 279 | Joanne Cuddihy | | 50.73 | | 27 ago 2007 | Yanmar Stadium Nagai, Osaka (JPN) |
| 279 | Yuliya Sotnikova | | 50.73 | | 24 jul 2000 | Tula (RUS) |
| 283 | Suziann Reid | | 50.74 | | 2 jul 1999 | Stade Olympique de la Pontaise, Lausanne (SUI) |
| 283 | Christine Mallard | | 50.74 | | 9 jul 2023 | Hayward Field, Eugene, OR (USA) |
| 283 | Junelle Bromfield | | 50.74 | | 29 jun 2024 | National Stadium, Kingston (JAM) |
| 286 | Ama Pipi | | 50.75 | | 20 jul 2023 | Štadión SNP, Banská Bystrica (SVK) |
| 286 | Joslyn Hoyte-Smith | | 50.75 | | 18 jun 1982 | London (GBR) |
| 288 | Keshia Kirtz | | 50.76 | | 16 may 2010 | Berkeley, CA (USA) |
| 288 | Anna Polinari |  | 50.76 | | 27 jun 2025 | Estadio Vallehermoso, Madrid (ESP) |
| 288 | Janieve Russell | | 50.76 | | 9 jul 2023 | National Stadium, Kingston (JAM) |
| 288 | Anneisha Mclaughlin-Whilby | | 50.76 | | 25 jun 2017 | Kingston (JAM) |
| 288 | Emma Zapletalová |  | 50.76 | | 28 jun 2025 | Atletski stadion Poljane, Maribor (SLO) |
| 293 | Lisanne De Witte |  | 50.77 | | 11 ago 2018 | Olympiastadion, Berlin (GER) |
| 293 | Yelena Didilenko-Korban | | 50.77 | | 27 jul 1983 | Leningrad (URS) |
| 295 | Olga Mineyeva | | 50.78 | | - | - |
| 295 | Gisela Anton | | 50.78 | | 27 jul 1976 | Halle (GER) |
| 295 | Michelle Lock |  | 50.78 | | 3 ago 1992 | Estadio Olímpico, Barcelona (ESP) |
| 295 | Leah Anderson | | 50.78 | | 29 jun 2025 | National Stadium, Kingston (JAM) |
| 295 | Lina Nielsen | | 50.78 | | 14 jul 2024 | Stade de La Charrière, La Chaux-de-Fonds (SUI) |
| 295 | Brionna Thomas | | 50.78 | | 9 jun 2018 | Eugene, OR (USA) |
